Our bodies are complex. 3X4 looks at how our genes work together in cellular pathways and functional systems to control processes such as inflammation, metabolism and detoxification. 

The science behind 3X4 is based on extensive research, combined with clinical practice to ensure that every recommendation made is both scientifically accurate and proven to work in clinical practice.

This test looks at the relationships between your genes in 36 metabolic pathways in your body. This approach ensures you get comprehensive feedback with explanations, recommendations and guidelines that are unique to you. Genetics make up the baseline “code” by which your body functions. The impact of every single choice you make throughout your life is influenced by your personal genetic makeup. Over 134 genes are tested that can affect your metabolism, inflammation, detoxification, fitness, weight, hormones, cognition, and response to your diet and supplements. By understanding how your unique genetics impact these key processes, you can make smarter, more personalized decisions about your health. There may even insights you never imagined (like whether that second cup of coffee is a good idea)!

Reports Included:

Core Age Tracking
◦ Epigenetic Biological Age | Your Whole-Body Summary
◦ Telomere Length | Aging based on cellular replication
◦ Dunedin PACE | A speedometer for your current rate of aging

What changes Biological Age?

     Epigenetic markers for Biological Age first start to change while you’re still in the womb, and continue to change throughout your entire life.

     These changes happen in response to nearly every choice you make. Nutrition, exercise habits, medications, injuries, environmental pollutions, how much sleep you’re getting, the stress you’re enduring, and much more. 

      It’s a long list, but recent studies have found that changing those factors can also change your Biological Age in as little as 8 weeks.

Why Measure Age?

     Ever wonder why some people look and act 10 years younger than they are? 

     A person's Epigenetic Age matters far more than the number of candles on their birthday cake, when it comes to estimating their health and age-related disease risks.

     Aging itself is the gradual loss of function at a cellular and molecular level. Epigenetics play a big part in regulating and controlling those functions, so it also plays a big part in aging. 

Accelerated epigenetic aging is actually the #1 risk factor for developing most age-related chronic diseases. With the  TruAge test kit, you can measure your epigenetic aging, and use our reports as a reference point to begin tracking how your lifestyle changes are affecting your aging at a molecular level. 

Telomere length is affected by both genetic and epigenetic contributions. A new study found that DNA methylation is closely linked to TL. The study by researchers at the University of California Los Angeles shows a very significant linkage between two different markers that indicate aging.

Telomeres are an essential part of human cells that affect how our cells age. Telomere length has emerged as an important determinant of replicative senescence and cell fate - an important indicator of the aging process and a wide range of disease states, including cancers, cardiovascular disease, and age-related disorders.

     Shorter telomeres are not only associated with age but with disease too. In fact, shorter telomere length and low telomerase
activity are associated with several chronic preventable diseases. These include hypertension, cardiovascular disease, insulin resistance, type 2 diabetes, depression, osteoporosis, and obesity.

     Shorter telomeres have also been implicated in genomic instability and oncogenesis. Older people with shorter telomeres have three and eight times increased risk of dying from heart and infectious diseases, respectively.

     The rate of telomere shortening and telomere length is therefore critical to an individual’s health and pace of aging.